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Neutralizing antibodies targeting a novel epitope on envelope protein exhibited broad protection against flavivirus without risk of disease enhancement

BACKGROUND: Flavivirus causes many serious public health problems worldwide. However, licensed DENV vaccine has restrictions on its use, and there is currently no approved ZIKV vaccine. Development of a potent and safe flavivirus vaccine is urgently needed. As a previous study revealed the epitope,...

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Detalles Bibliográficos
Autores principales: Yen, Li-Chen, Chen, Hsin-Wei, Ho, Chia-Lo, Lin, Chang-Chi, Lin, Yi-Ling, Yang, Qiao-Wen, Chiu, Kuo-Chou, Lien, Shu-Pei, Lin, Ren-Jye, Liao, Ching-Len
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265553/
https://www.ncbi.nlm.nih.gov/pubmed/37316861
http://dx.doi.org/10.1186/s12929-023-00938-y