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Neutralizing antibodies targeting a novel epitope on envelope protein exhibited broad protection against flavivirus without risk of disease enhancement
BACKGROUND: Flavivirus causes many serious public health problems worldwide. However, licensed DENV vaccine has restrictions on its use, and there is currently no approved ZIKV vaccine. Development of a potent and safe flavivirus vaccine is urgently needed. As a previous study revealed the epitope,...
Autores principales: | Yen, Li-Chen, Chen, Hsin-Wei, Ho, Chia-Lo, Lin, Chang-Chi, Lin, Yi-Ling, Yang, Qiao-Wen, Chiu, Kuo-Chou, Lien, Shu-Pei, Lin, Ren-Jye, Liao, Ching-Len |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265553/ https://www.ncbi.nlm.nih.gov/pubmed/37316861 http://dx.doi.org/10.1186/s12929-023-00938-y |
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