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Prognostic role and interaction of TERT promoter status, telomere length and MGMT promoter methylation in newly diagnosed IDH wild-type glioblastoma patients

BACKGROUND: The clinical relevance of promoter mutations and single nucleotide polymorphism rs2853669 of telomerase reverse transcriptase (TERT) and telomere length in patients with isocitrate dehydrogenase (IDH) wild-type glioblastoma (GBM) patients remains unclear. Moreover, some studies speculate...

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Detalles Bibliográficos
Autores principales: Giunco, S., Padovan, M., Angelini, C., Cavallin, F., Cerretti, G., Morello, M., Caccese, M., Rizzo, B., d’Avella, D., Puppa, A.D., Chioffi, F., De Bonis, P., Zagonel, V., De Rossi, A., Lombardi, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265608/
https://www.ncbi.nlm.nih.gov/pubmed/37230028
http://dx.doi.org/10.1016/j.esmoop.2023.101570