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Peptide Antibiotic–Polyphosphate Nanoparticles: A Promising Strategy to Overcome the Enzymatic and Mucus Barrier of the Intestine

[Image: see text] The aim of this study was to develop peptide antibiotic–polyphosphate nanoparticles that are able to overcome the enzymatic and mucus barriers providing a targeted drug release directly on the intestinal epithelium. Polymyxin B–polyphosphate nanoparticles (PMB–PP NPs) were formed v...

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Detalles Bibliográficos
Autores principales: Saleh, Ahmad, Akkuş-Dağdeviren, Zeynep Burcu, Haddadzadegan, Soheil, Wibel, Richard, Bernkop-Schnürch, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265664/
https://www.ncbi.nlm.nih.gov/pubmed/37224061
http://dx.doi.org/10.1021/acs.biomac.3c00083