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A partitioned 88-loci psoriasis genetic risk score reveals HLA and non-HLA contributions to clinical phenotypes in a Newfoundland psoriasis cohort

Psoriasis is an immune-mediated inflammatory skin disease typically characterized by erythematous and scaly plaques. It affects 3% of the Newfoundland population while only affecting 1.7% of the general Canadian population. Recent genome-wide association studies (GWAS) in psoriasis have identified m...

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Detalles Bibliográficos
Autores principales: Bui, Audrey, Kumar, Sugandh, Liu, Jared, Orcales, Faye, Gulliver, Susanne, Tsoi, Lam C., Gulliver, Wayne, Liao, Wilson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265743/
https://www.ncbi.nlm.nih.gov/pubmed/37323656
http://dx.doi.org/10.3389/fgene.2023.1141010