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Multivariate modular metabolic engineering for enhanced l-methionine biosynthesis in Escherichia coli

BACKGROUND: l-Methionine is the only bulk amino acid that has not been industrially produced by the fermentation method. Due to highly complex and strictly regulated biosynthesis, the development of microbial strains for high-level l-methionine production has remained challenging in recent years. RE...

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Detalles Bibliográficos
Autores principales: Li, Zhongcai, Liu, Qian, Sun, Jiahui, Sun, Jianjian, Li, Mingjie, Zhang, Yun, Deng, Aihua, Liu, Shuwen, Wen, Tingyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265765/
https://www.ncbi.nlm.nih.gov/pubmed/37312226
http://dx.doi.org/10.1186/s13068-023-02347-7