Inhibiting HIF-1 signaling alleviates HTRA1-induced RPE senescence in retinal degeneration

BACKGROUND: Age-related macular degeneration (AMD), characterized by the degeneration of retinal pigment epithelium (RPE) and photoreceptors, is the leading cause of irreversible vision impairment among the elderly. RPE senescence is an important contributor to AMD and has become a potential target...

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Detalles Bibliográficos
Autores principales: Xu, Wenchang, Liu, Xinqi, Han, Wenjuan, Wu, Keling, Zhao, Minglei, Mei, Tingfang, Shang, Bizhi, Wu, Jinwen, Luo, Jingyi, Lai, Yuhua, Yang, Boyu, Zhuo, Yehong, Lu, Lin, Liu, Yizhi, Tian, Xiao-li, Zhao, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265780/
https://www.ncbi.nlm.nih.gov/pubmed/37316948
http://dx.doi.org/10.1186/s12964-023-01138-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265780/
https://www.ncbi.nlm.nih.gov/pubmed/37316948
http://dx.doi.org/10.1186/s12964-023-01138-9

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