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RegCloser: a robust regression approach to closing genome gaps

BACKGROUND: Closing gaps in draft genomes leads to more complete and continuous genome assemblies. The ubiquitous genomic repeats are challenges to the existing gap-closing methods, based on either the k-mer representation by the de Bruijn graph or the overlap-layout-consensus paradigm. Besides, chi...

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Detalles Bibliográficos
Autores principales: Cao, Shenghao, Li, Mengtian, Li, Lei M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265787/
https://www.ncbi.nlm.nih.gov/pubmed/37312038
http://dx.doi.org/10.1186/s12859-023-05367-0