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Tamoxifen decreases ovarian toxicity without compromising cancer treatment in a rat model of mammary cancer

BACKGROUND: Premenopausal women diagnosed with breast cancer often face aggressive chemotherapy resulting in infertility. Tamoxifen (TAM) is a selective estrogen receptor modulator that was previously suggested as a protective agent against chemotherapy-induced ovarian failure. In the current study,...

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Detalles Bibliográficos
Autores principales: Nynca, Anna, Swigonska, Sylwia, Ruszkowska, Monika, Sadowska, Agnieszka, Orlowska, Karina, Molcan, Tomasz, Myszczynski, Kamil, Otrocka-Domagala, Iwona, Paździor-Czapula, Katarzyna, Kurowicka, Beata, Petroff, Brian Kelli, Ciereszko, Renata Elzbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265842/
https://www.ncbi.nlm.nih.gov/pubmed/37312040
http://dx.doi.org/10.1186/s12864-023-09423-0