Cargando…

Tamoxifen decreases ovarian toxicity without compromising cancer treatment in a rat model of mammary cancer

BACKGROUND: Premenopausal women diagnosed with breast cancer often face aggressive chemotherapy resulting in infertility. Tamoxifen (TAM) is a selective estrogen receptor modulator that was previously suggested as a protective agent against chemotherapy-induced ovarian failure. In the current study,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nynca, Anna, Swigonska, Sylwia, Ruszkowska, Monika, Sadowska, Agnieszka, Orlowska, Karina, Molcan, Tomasz, Myszczynski, Kamil, Otrocka-Domagala, Iwona, Paździor-Czapula, Katarzyna, Kurowicka, Beata, Petroff, Brian Kelli, Ciereszko, Renata Elzbieta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265842/ https://www.ncbi.nlm.nih.gov/pubmed/37312040 http://dx.doi.org/10.1186/s12864-023-09423-0

Ejemplares similares

Molecular Action of Tamoxifen in the Ovaries of Rats with Mammary Neoplasia
por: Nynca, Anna, et al.
Publicado: (2023)

Proteomic changes of aryl hydrocarbon receptor (AhR)-silenced porcine granulosa cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
por: Orlowska, Karina, et al.
Publicado: (2019)

Identification and characterization of long non-coding RNAs in porcine granulosa cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin
por: Ruszkowska, Monika, et al.
Publicado: (2018)

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the transcriptome of aryl hydrocarbon receptor (AhR) knock-down porcine granulosa cells
por: Ruszkowska, Monika, et al.
Publicado: (2020)

The involvement of CYP1A2 in biodegradation of dioxins in pigs
por: Swigonska, Sylwia, et al.
Publicado: (2022)

Dexamethasone-induced impairment of post-injury skeletal muscle regeneration
por: Otrocka-Domagała, Iwona, et al.
Publicado: (2019)

Simvastatin Impairs the Inflammatory and Repair Phases of the Postinjury Skeletal Muscle Regeneration
por: Otrocka-Domagała, Iwona, et al.
Publicado: (2018)

Morphology and immunophenotype of canine cutaneous histiocytic tumours with particular emphasis on diagnostic application
por: Paździor-Czapula, Katarzyna, et al.
Publicado: (2014)

Metallothionein expression in feline injection site fibrosarcomas
por: Mikiewicz, Mateusz, et al.
Publicado: (2023)

Cutaneous and Subcutaneous Tumours of Small Pet Mammals—Retrospective Study of 256 Cases (2014–2021)
por: Otrocka-Domagała, Iwona, et al.
Publicado: (2022)

Association between Enzootic Pneumonia-Like Lung Lesions and Carcass Quality and Meat pH Value in Slaughter Pigs
por: Przyborowska-Zhalniarovich, Paulina, et al.
Publicado: (2023)

Chitosan/Phenolic Compounds Scaffolds for Connective Tissue Regeneration
por: Kaczmarek-Szczepańska, Beata, et al.
Publicado: (2023)

The combined effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and the phytoestrogen genistein on steroid hormone secretion, AhR and ERβ expression and the incidence of apoptosis in granulosa cells of medium porcine follicles
por: PIASECKA-SRADER, Joanna, et al.
Publicado: (2015)

The characterization of collagen-based scaffolds modified with phenolic acids for tissue engineering application
por: Kaczmarek-Szczepańska, Beata, et al.
Publicado: (2023)

Characteristics and Cryopreservation of Semen of Sex-Reversed Females of Salmonid Fish
por: Judycka, Sylwia, et al.
Publicado: (2021)

Application of two-dimensional difference gel electrophoresis to identify protein changes between center, margin, and adjacent non-tumor tissues obtained from non-small-cell lung cancer with adenocarcinoma or squamous cell carcinoma subtype
por: Ciereszko, Andrzej, et al.
Publicado: (2022)

The Effect of 42-Day Exposure to a Low Deoxynivalenol Dose on the Immunohistochemical Expression of Intestinal ERs and the Activation of CYP1A1 and GSTP1 Genes in the Large Intestine of Pre-pubertal Gilts
por: Gajęcka, Magdalena, et al.
Publicado: (2021)

Two different clinical forms of squamous cell carcinoma (SCC) in the perineum and vulva of two mares
por: Raś, Andrzej, et al.
Publicado: (2020)

Immunohistochemical Expression (IE) of Oestrogen Receptors in the Intestines of Prepubertal Gilts Exposed to Zearalenone
por: Gajęcka, Magdalena, et al.
Publicado: (2023)

Patterns of Diversity of Fusarium Fungi Contaminating Soybean Grains
por: Żelechowski, Maciej, et al.
Publicado: (2021)

The influence of tamoxifen on normal mouse mammary gland homeostasis
por: Shehata, Mona, et al.
Publicado: (2014)

Influence of deoxynivalenol and zearalenone on the immunohistochemical expression of oestrogen receptors and liver enzyme genes in vivo in prepubertal gilts
por: Gajęcka, Magdalena, et al.
Publicado: (2023)

Uncovering Diagnostic Value of Mitogenome for Identification of Cryptic Species Fusarium graminearum Sensu Stricto
por: Wyrębek, Joanna, et al.
Publicado: (2021)

Immunopathology of Parasitic Infections and Therapeutic Approaches in Humans and Animals
por: Paciello, Orlando, et al.
Publicado: (2016)

Optimised analysis of tamoxifen and its main metabolites in the plasma and cytosol of mammary tumours.
por: Milano, G., et al.
Publicado: (1987)

Effects of Ginkgo biloba on chemically-induced mammary tumors in rats receiving tamoxifen
por: Dias, Marcos Correa, et al.
Publicado: (2013)

Chemoprevention of N‐Nitroso‐N‐methylurea‐induced Rat Mammary Cancer by Miso and Tamoxifen, Alone and in Combination
por: Gotoh, Takahiko, et al.
Publicado: (1998)

Enhanced anti-mammary gland cancer activities of tamoxifen-loaded erythropoietin-coated drug delivery system
por: Beh, Chaw Yee, et al.
Publicado: (2019)

Identification of protein changes in the blood plasma of lung cancer patients subjected to chemotherapy using a 2D-DIGE approach
por: Ciereszko, Andrzej, et al.
Publicado: (2019)

Mutations of p53 Gene in Canine Sweat Gland Carcinomas Probably Associated with UV Radiation
por: Jasik, Agnieszka, et al.
Publicado: (2021)

Diffusion Weighted Imaging Evaluated the Early Therapy Effect of Tamoxifen in an MNU-Induced Mammary Cancer Rat Model
por: Zhai, Guihua, et al.
Publicado: (2013)

Immunopathological Features of Canine Myocarditis Associated with Leishmania infantum Infection
por: Costagliola, Alessandro, et al.
Publicado: (2016)

Monitoring therapeutic response to tamoxifen in NMU-induced rat mammary tumours by 31P MRS.
por: Baluch, S., et al.
Publicado: (1991)

Idoxifene is equipotent to tamoxifen in inhibiting mammary carcinogenesis but forms lower levels of hepatic DNA adducts.
por: Pace, P., et al.
Publicado: (1997)

Tamoxifen induces pleiotrophic changes in mammary stroma resulting in extracellular matrix that suppresses transformed phenotypes
por: Hattar, Rhonda, et al.
Publicado: (2009)

Therapeutic Effects of a Traditional Chinese Medicine Formula Plus Tamoxifen vs. Tamoxifen for the Treatment of Mammary Gland Hyperplasia: A Meta-Analysis of Randomized Trials
por: Li, Hao-Tian, et al.
Publicado: (2018)

Flutamide-induced alterations in transcriptional profiling of neonatal porcine ovaries
por: Knapczyk-Stwora, Katarzyna, et al.
Publicado: (2019)

Potential of Transcript Editing Across Mitogenomes of Early Land Plants Shows Novel and Familiar Trends
por: Myszczyński, Kamil, et al.
Publicado: (2019)

Resuming Sensitivity of Tamoxifen-Resistant Breast Cancer Cells to Tamoxifen by Tetrandrine
por: Wang, Yuntao, et al.
Publicado: (2021)

Influence of Tamoxifen on Different Biological Pathways in Tumorigenesis and Transformation in Adipose-Derived Stem Cells, Mammary Cells and Mammary Carcinoma Cell Lines—An In Vitro Study
por: Schlottmann, Frederik, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0jq6rms4m516q8bm02l3dp1cnf