Estrogen receptor blockade and radiation therapy cooperate to enhance the response of immunologically cold ER+ breast cancer to immunotherapy

BACKGROUND: Most patients with estrogen receptor positive (ER+) breast cancer do not respond to immune checkpoint inhibition (ICI); the tumor microenvironment (TME) of these cancers is generally immunosuppressive and contains few tumor-infiltrating lymphocytes. Radiation therapy (RT) can increase tu...

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Detalles Bibliográficos
Autores principales: O’Leary, Kathleen A., Bates, Amber M., Jin, Won Jong, Burkel, Brian M., Sriramaneni, Raghava N., Emma, Sarah E., Nystuen, Erin J., Sumiec, Elizabeth G., Ponik, Suzanne M., Morris, Zachary S., Schuler, Linda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265911/
https://www.ncbi.nlm.nih.gov/pubmed/37312163
http://dx.doi.org/10.1186/s13058-023-01671-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265911/
https://www.ncbi.nlm.nih.gov/pubmed/37312163
http://dx.doi.org/10.1186/s13058-023-01671-y

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