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SARS-CoV-2 ORF3c impairs mitochondrial respiratory metabolism, oxidative stress, and autophagic flux

Coronaviruses encode a variable number of accessory proteins that are involved in host-virus interaction, suppression of immune responses, or immune evasion. SARS-CoV-2 encodes at least twelve accessory proteins, whose roles during infection have been studied. Nevertheless, the role of the ORF3c acc...

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Detalles Bibliográficos
Autores principales: Mozzi, Alessandra, Oldani, Monica, Forcella, Matilde E., Vantaggiato, Chiara, Cappelletti, Gioia, Pontremoli, Chiara, Valenti, Francesca, Forni, Diego, Saresella, Marina, Biasin, Mara, Sironi, Manuela, Fusi, Paola, Cagliani, Rachele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265927/
https://www.ncbi.nlm.nih.gov/pubmed/37361873
http://dx.doi.org/10.1016/j.isci.2023.107118