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Intranasal delivery of an adenovirus-vector vaccine co-expressing a modified spike protein and a genetic adjuvant confers lasting mucosal immunity against SARS-CoV-2

The ongoing COVID-19 pandemic caused by SARS-CoV-2 infection has threatened global health. Since the first case of infection was reported in December 2019, SARS-CoV-2 has rapidly spread worldwide and caused millions of deaths. As vaccination is the best way to protect the host from invading pathogen...

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Detalles Bibliográficos
Autores principales: Jung, Hi Eun, Ku, Keun Bon, Kang, Byeong Hoon, Park, Jang Hyun, Kim, Hyeon Cheol, Kim, Kyun-Do, Lee, Heung Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10265935/
https://www.ncbi.nlm.nih.gov/pubmed/37327877
http://dx.doi.org/10.1016/j.antiviral.2023.105656