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17β-estradiol promotes extracellular vesicle release and selective miRNA loading in ERα-positive breast cancer

The causes and consequences of abnormal biogenesis of extracellular vesicles (EVs) are not yet well understood in malignancies, including in breast cancers (BCs). Given the hormonal signaling dependence of estrogen receptor–positive (ER+) BC, we hypothesized that 17β-estradiol (estrogen) might influ...

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Detalles Bibliográficos
Autores principales: Drula, Rares, Pardini, Barbara, Fu, Xiao, De los Santos, Mireia Cruz, Jurj, Ancuta, Pang, Lan, El-Daly, Sherien M., Fabris, Linda, Knutsen, Erik, Dragomir, Mihnea P., Bayraktar, Recep, Li, Yongfeng, Chen, Meng, Del Vecchio, Filippo, Berland, Léa, Dae, Jessica, Fan, Daniel, Shimizu, Masayoshi, Tran, Anh M., Barzi, Mercedes, Pioppini, Carlotta, Gutierrez, Angelica M., Ivan, Cristina, Meas, Salyna, Hall, Carolyn S., Alahari, Suresh K., Berindan-Neagoe, Ioana, Fabbri, Muller, Lucci, Anthony, Arun, Banu, Anfossi, Simone, Calin, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266002/
https://www.ncbi.nlm.nih.gov/pubmed/37252969
http://dx.doi.org/10.1073/pnas.2122053120