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Calcium dynamics at the neural cell primary cilium regulate Hedgehog signaling–dependent neurogenesis in the embryonic neural tube

The balance between neural stem cell proliferation and neuronal differentiation is paramount for the appropriate development of the nervous system. Sonic hedgehog (Shh) is known to sequentially promote cell proliferation and specification of neuronal phenotypes, but the signaling mechanisms responsi...

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Detalles Bibliográficos
Autores principales: Shim, Sangwoo, Goyal, Raman, Panoutsopoulos, Alexios A., Balashova, Olga A., Lee, David, Borodinsky, Laura N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266006/
https://www.ncbi.nlm.nih.gov/pubmed/37252980
http://dx.doi.org/10.1073/pnas.2220037120