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Calcium dynamics at the neural cell primary cilium regulate Hedgehog signaling–dependent neurogenesis in the embryonic neural tube
The balance between neural stem cell proliferation and neuronal differentiation is paramount for the appropriate development of the nervous system. Sonic hedgehog (Shh) is known to sequentially promote cell proliferation and specification of neuronal phenotypes, but the signaling mechanisms responsi...
Autores principales: | Shim, Sangwoo, Goyal, Raman, Panoutsopoulos, Alexios A., Balashova, Olga A., Lee, David, Borodinsky, Laura N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266006/ https://www.ncbi.nlm.nih.gov/pubmed/37252980 http://dx.doi.org/10.1073/pnas.2220037120 |
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