Sex-specific and opposed effects of FKBP51 in glutamatergic and GABAergic neurons: Implications for stress susceptibility and resilience

Mental health disorders often arise as a combination of environmental and genetic factors. The FKBP5 gene, encoding the GR co-chaperone FKBP51, has been uncovered as a key genetic risk factor for stress-related illness. However, the exact cell type and region-specific mechanisms by which FKBP51 cont...

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Detalles Bibliográficos
Autores principales: van Doeselaar, Lotte, Stark, Tibor, Mitra, Shiladitya, Yang, Huanqing, Bordes, Joeri, Stolwijk, Linda, Engelhardt, Clara, Kovarova, Veronika, Narayan, Sowmya, Brix, Lea M., Springer, Margherita, Deussing, Jan M., Lopez, Juan Pablo, Czisch, Michael, Schmidt, Mathias V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266018/
https://www.ncbi.nlm.nih.gov/pubmed/37252963
http://dx.doi.org/10.1073/pnas.2300722120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266018/
https://www.ncbi.nlm.nih.gov/pubmed/37252963
http://dx.doi.org/10.1073/pnas.2300722120

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