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Cis-inhibition suppresses basal Notch signaling during sensory organ precursor selection

The emergence of the sensory organ precursor (SOP) from an equivalence group in Drosophila is a paradigm for studying single-cell fate specification through Notch-mediated lateral inhibition. Yet, it remains unclear how only a single SOP is selected from a relatively large group of cells. We show he...

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Detalles Bibliográficos
Autores principales: Troost, Tobias, Binshtok, Udi, Sprinzak, David, Klein, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266033/
https://www.ncbi.nlm.nih.gov/pubmed/37252950
http://dx.doi.org/10.1073/pnas.2214535120