HIV-1 usurps transcription start site heterogeneity of host RNA polymerase II to maximize replication fitness

HIV-1 relies on host RNA polymeraseII (Pol II) to transcribe its genome and uses multiple transcription start sites (TSS), including three consecutive guanosines located near the U3-R junction, to generate transcripts containing three, two, and one guanosine at the 5′ end, referred to as 3G, 2G, and...

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Detalles Bibliográficos
Autores principales: Nikolaitchik, Olga A., Islam, Saiful, Kitzrow, Jonathan P., Duchon, Alice, Cheng, Zetao, Liu, Yang, Rawson, Jonathan M. O., Shao, Wei, Nikolaitchik, Maria, Kearney, Mary F., Maldarelli, Frank, Musier-Forsyth, Karin, Pathak, Vinay K., Hu, Wei-Shau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266039/
https://www.ncbi.nlm.nih.gov/pubmed/37252967
http://dx.doi.org/10.1073/pnas.2305103120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266039/
https://www.ncbi.nlm.nih.gov/pubmed/37252967
http://dx.doi.org/10.1073/pnas.2305103120

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