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Theory of chromatin organization maintained by active loop extrusion

The active loop extrusion hypothesis proposes that chromatin threads through the cohesin protein complex into progressively larger loops until reaching specific boundary elements. We build upon this hypothesis and develop an analytical theory for active loop extrusion which predicts that loop format...

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Detalles Bibliográficos
Autores principales: Chan, Brian, Rubinstein, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266055/
https://www.ncbi.nlm.nih.gov/pubmed/37253009
http://dx.doi.org/10.1073/pnas.2222078120