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Theory of chromatin organization maintained by active loop extrusion
The active loop extrusion hypothesis proposes that chromatin threads through the cohesin protein complex into progressively larger loops until reaching specific boundary elements. We build upon this hypothesis and develop an analytical theory for active loop extrusion which predicts that loop format...
Autores principales: | Chan, Brian, Rubinstein, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266055/ https://www.ncbi.nlm.nih.gov/pubmed/37253009 http://dx.doi.org/10.1073/pnas.2222078120 |
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