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Melatonin regulates microglial polarization to M2 cell via RhoA/ROCK signaling pathway in epilepsy

BACKGROUND: Melatonin (MEL), an endogenous hormone, has been widely investigated in neurological diseases. Microglia (MG), a resident immunocyte localizing in central nervous system is reported to play important functions in the animal model of temporal lobe epilepsy (TLE). Some evidence showed that...

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Detalles Bibliográficos
Autores principales: Li, Pingping, Ji, Xuefei, Shan, Ming, Wang, Yi, Dai, Xingliang, Yin, Mengyuan, Liu, Yunlong, Guan, Liao, Ye, Lei, Cheng, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266134/
https://www.ncbi.nlm.nih.gov/pubmed/37382264
http://dx.doi.org/10.1002/iid3.900