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Interferon beta treatment is a potent and targeted epigenetic modifier in multiple sclerosis

INTRODUCTION: Multiple Sclerosis (MS) has a complex pathophysiology that involves genetic and environmental factors. DNA methylation (DNAm) is one epigenetic mechanism that can reversibly modulate gene expression. Cell specific DNAm changes have been associated with MS, and some MS therapies such as...

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Detalles Bibliográficos
Autores principales: Xavier, Alexandre, Campagna, Maria Pia, Maltby, Vicki E., Kilpatrick, Trevor, Taylor, Bruce V., Butzkueven, Helmut, Ponsonby, Anne-Louise, Scott, Rodney J., Jokubaitis, Vilija G., Lea, Rodney A., Lechner-Scott, Jeannette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266220/
https://www.ncbi.nlm.nih.gov/pubmed/37325639
http://dx.doi.org/10.3389/fimmu.2023.1162796