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Sialidase facilitates Porphyromonas gingivalis immune evasion by reducing M1 polarization, antigen presentation, and phagocytosis of infected macrophages

BACKGROUND: Porphyromonas gingivalis (P. gingivalis), a major pathogen of periodontitis, can evade host immune defenses. Previously, we found that P. gingivalis W83 sialidase gene mutant strain (ΔPG0352) was more easily cleared by macrophages. The aims of this study were to investigate the effects o...

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Detalles Bibliográficos
Autores principales: Fan, Xiaomiao, Zheng, Shaowen, Chen, Chen, Lin, Li, Wang, Hongyan, Shen, Yuqin, Pan, Yaping, Li, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266273/
https://www.ncbi.nlm.nih.gov/pubmed/37325520
http://dx.doi.org/10.3389/fcimb.2023.1173899