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HIV-1 activates oxidative phosphorylation in infected CD4 T cells in a human tonsil explant model

INTRODUCTION: Human immunodeficiency virus type 1 (HIV-1) causes a chronic, incurable infection leading to immune activation and chronic inflammation in people with HIV-1 (PWH), even with virologic suppression on antiretroviral therapy (ART). The role of lymphoid structures as reservoirs for viral l...

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Detalles Bibliográficos
Autores principales: Freeman, Tracey L., Zhao, Connie, Schrode, Nadine, Fortune, Trinisia, Shroff, Sanjana, Tweel, Benjamin, Beaumont, Kristin G., Swartz, Talia H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266353/
https://www.ncbi.nlm.nih.gov/pubmed/37325659
http://dx.doi.org/10.3389/fimmu.2023.1172938