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Myeloid-Specific SIRT6 Deletion Protects Against Particulate Matter (PM(2.5))-Induced Airway Inflammation

PURPOSE: Particulate matter (PM(2.5)) is a common risk factor for airway inflammation. Alveolar macrophages play a critical role in airway inflammation. Sirtuin 6 (SIRT6) is a class Ill histone deacetylase that exerts an anti-inflammatory effect in airway diseases. However, the role of SIRT6 on PM2....

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Detalles Bibliográficos
Autores principales: Chen, Shaopeng, Wu, Mindan, Xiong, Zhilin, Huang, Jiewen, Lv, Yingying, Li, Yuyan, Zeng, Minjuan, Lai, Tianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266380/
https://www.ncbi.nlm.nih.gov/pubmed/37323542
http://dx.doi.org/10.2147/COPD.S398796