Cargando…

Mitochondria Transfer from Mesenchymal Stem Cells Confers Chemoresistance to Glioblastoma Stem Cells through Metabolic Rewiring

Glioblastomas (GBM) are heterogeneous tumors with high metabolic plasticity. Their poor prognosis is linked to the presence of glioblastoma stem cells (GSC), which support resistance to therapy, notably to temozolomide (TMZ). Mesenchymal stem cells (MSC) recruitment to GBM contributes to GSC chemore...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakhle, Jean, Khattar, Khattar, Özkan, Tülin, Boughlita, Adel, Abba Moussa, Daouda, Darlix, Amélie, Lorcy, Frédérique, Rigau, Valérie, Bauchet, Luc, Gerbal-Chaloin, Sabine, Daujat-Chavanieu, Martine, Bellvert, Floriant, Turchi, Laurent, Virolle, Thierry, Hugnot, Jean-Philippe, Buisine, Nicolas, Galloni, Mireille, Dardalhon, Valérie, Rodriguez, Anne-Marie, Vignais, Marie-Luce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266428/
https://www.ncbi.nlm.nih.gov/pubmed/37377608
http://dx.doi.org/10.1158/2767-9764.CRC-23-0144