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Mitochondria Transfer from Mesenchymal Stem Cells Confers Chemoresistance to Glioblastoma Stem Cells through Metabolic Rewiring
Glioblastomas (GBM) are heterogeneous tumors with high metabolic plasticity. Their poor prognosis is linked to the presence of glioblastoma stem cells (GSC), which support resistance to therapy, notably to temozolomide (TMZ). Mesenchymal stem cells (MSC) recruitment to GBM contributes to GSC chemore...
Autores principales: | Nakhle, Jean, Khattar, Khattar, Özkan, Tülin, Boughlita, Adel, Abba Moussa, Daouda, Darlix, Amélie, Lorcy, Frédérique, Rigau, Valérie, Bauchet, Luc, Gerbal-Chaloin, Sabine, Daujat-Chavanieu, Martine, Bellvert, Floriant, Turchi, Laurent, Virolle, Thierry, Hugnot, Jean-Philippe, Buisine, Nicolas, Galloni, Mireille, Dardalhon, Valérie, Rodriguez, Anne-Marie, Vignais, Marie-Luce |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266428/ https://www.ncbi.nlm.nih.gov/pubmed/37377608 http://dx.doi.org/10.1158/2767-9764.CRC-23-0144 |
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