CD8(+) T cell depletion prevents neuropathology in a mouse model of globoid cell leukodystrophy

Globoid cell leukodystrophy (GLD) or Krabbe’s disease is a fatal genetic demyelinating disease of the central nervous system caused by loss-of-function mutations in the galactosylceramidase (galc) gene. While the metabolic basis for disease is known, the understanding of how this results in neuropat...

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Detalles Bibliográficos
Autores principales: Sutter, Pearl A., Ménoret, Antoine, Jellison, Evan R., Nicaise, Alexandra M., Bradbury, Allison M., Vella, Anthony T., Bongarzone, Ernesto R., Crocker, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266545/
https://www.ncbi.nlm.nih.gov/pubmed/37310382
http://dx.doi.org/10.1084/jem.20221862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266545/
https://www.ncbi.nlm.nih.gov/pubmed/37310382
http://dx.doi.org/10.1084/jem.20221862

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