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Brucella abortus modulates macrophage polarization and inflammatory response by targeting glutaminases through the NF-κB signaling pathway

OBJECTIVES: The mechanism of Brucella infection regulating macrophage phenotype has not been completely elucidated until now. This study aimed to determine the mechanism of Brucella abortus in the modulation of macrophage phenotype using RAW264.7 cells as a model. MATERIALS AND METHODS: RT-qPCR, ELI...

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Detalles Bibliográficos
Autores principales: Zhao, Tianyi, Zhang, Zedan, Li, Yitao, Sun, Zhihua, Liu, Liangbo, Deng, Xingmei, Guo, Jia, Zhu, Dexin, Cao, Shuzhu, Chai, Yingjin, Nikolaevna, Usevich Vera, Maratbek, Suleimenov, Wang, Zhen, Zhang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266586/
https://www.ncbi.nlm.nih.gov/pubmed/37325614
http://dx.doi.org/10.3389/fimmu.2023.1180837