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A polycistronic transgene design for combinatorial genetic perturbations from a single transcript in Drosophila
Experimental models that capture the genetic complexity of human disease and allow mechanistic explorations of the underlying cell, tissue, and organ interactions are crucial to furthering our understanding of disease biology. Such models require combinatorial manipulations of multiple genes, often...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266610/ https://www.ncbi.nlm.nih.gov/pubmed/37267433 http://dx.doi.org/10.1371/journal.pgen.1010792 |