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A polycistronic transgene design for combinatorial genetic perturbations from a single transcript in Drosophila

Experimental models that capture the genetic complexity of human disease and allow mechanistic explorations of the underlying cell, tissue, and organ interactions are crucial to furthering our understanding of disease biology. Such models require combinatorial manipulations of multiple genes, often...

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Detalles Bibliográficos
Autores principales: Teague, Alexander G., Quintero, Maria, Karimi Dermani, Fateme, Cagan, Ross L., Bangi, Erdem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266610/
https://www.ncbi.nlm.nih.gov/pubmed/37267433
http://dx.doi.org/10.1371/journal.pgen.1010792