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A mathematical model for cancer risk and accumulation of mutations caused by replication errors and external factors
Replication errors influence mutations, and thus, lifetime cancer risk can be explained by the number of stem-cell divisions. Additionally, mutagens also affect cancer risk, for instance, high-dose radiation exposure increases lifetime cancer risk. However, the influence of low-dose radiation exposu...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266611/ https://www.ncbi.nlm.nih.gov/pubmed/37315031 http://dx.doi.org/10.1371/journal.pone.0286499 |