A Bayesian approach to estimate the probability of resistance to bedaquiline in the presence of a genomic variant

BACKGROUND: Bedaquiline is a core drug for treatment of rifampicin-resistant tuberculosis. Few genomic variants have been statistically associated with bedaquiline resistance. Alternative approaches for determining the genotypic-phenotypic association are needed to guide clinical care. METHODS: Usin...

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Detalles Bibliográficos
Autores principales: Anlay, Degefaye Zelalem, Rivière, Emmanuel, Tu, Pham Hien Trang, Abrams, Steven, Van Rie, Annelies
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266631/
https://www.ncbi.nlm.nih.gov/pubmed/37315052
http://dx.doi.org/10.1371/journal.pone.0287019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266631/
https://www.ncbi.nlm.nih.gov/pubmed/37315052
http://dx.doi.org/10.1371/journal.pone.0287019

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