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A Bayesian approach to estimate the probability of resistance to bedaquiline in the presence of a genomic variant
BACKGROUND: Bedaquiline is a core drug for treatment of rifampicin-resistant tuberculosis. Few genomic variants have been statistically associated with bedaquiline resistance. Alternative approaches for determining the genotypic-phenotypic association are needed to guide clinical care. METHODS: Usin...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266631/ https://www.ncbi.nlm.nih.gov/pubmed/37315052 http://dx.doi.org/10.1371/journal.pone.0287019 |