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Yap controls notochord formation and neural tube patterning by integrating mechanotransduction with FoxA2 and Shh expression

Correct notochord and neural tube (NT) formation is crucial to the development of the central nervous system and midline structures. Integrated biochemical and biophysical signaling controls embryonic growth and patterning; however, the underlying mechanisms remain poorly understood. Here, we took t...

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Detalles Bibliográficos
Autores principales: Cheng, Caiqi, Cong, Qian, Liu, Yuchen, Hu, Yizhong, Liang, Guoyan, Dioneda, Kevin Marc Manquiquis, Yang, Yingzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266736/
https://www.ncbi.nlm.nih.gov/pubmed/37315133
http://dx.doi.org/10.1126/sciadv.adf6927