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Loss of STAT2 may be dangerous in a world filled with viruses

Type I IFNs, a family of cytokines that signal through a single receptor and signaling mechanism, were originally named for their ability to interfere with viral replication. While type II IFN (IFN-γ) largely protects against intracellular bacteria and protozoa, type I IFNs largely protect from vira...

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Detalles Bibliográficos
Autor principal: Jordan, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266770/
https://www.ncbi.nlm.nih.gov/pubmed/37317971
http://dx.doi.org/10.1172/JCI170886