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Negativity begets longevity in T cells
Killer immunoglobulin-like receptors (KIRs) are polymorphic receptors for human leukocyte antigens (HLAs) that provide positive or negative signals controlling lymphocyte activation. Expression of inhibitory KIRs by CD8(+) T cells affects their survival and function, which is linked to improved anti...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266772/ https://www.ncbi.nlm.nih.gov/pubmed/37317967 http://dx.doi.org/10.1172/JCI171027 |