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Increased cell senescence in human metabolic disorders

Cell senescence (CS) is at the nexus between aging and associated chronic disorders, and aging increases the burden of CS in all major metabolic tissues. However, CS is also increased in adult obesity, type 2 diabetes (T2D), and nonalcoholic fatty liver disease independent of aging. Senescent tissue...

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Detalles Bibliográficos
Autores principales: Spinelli, Rosa, Baboota, Ritesh Kumar, Gogg, Silvia, Beguinot, Francesco, Blüher, Matthias, Nerstedt, Annika, Smith, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266774/
https://www.ncbi.nlm.nih.gov/pubmed/37317964
http://dx.doi.org/10.1172/JCI169922