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Mechanism-based target therapy in primary biliary cholangitis: opportunities before liver cirrhosis?
Primary biliary cholangitis (PBC) is an immune-mediated liver disease characterized by cholestasis, biliary injuries, liver fibrosis, and chronic non-suppurative cholangitis. The pathogenesis of PBC is multifactorial and involves immune dysregulation, abnormal bile metabolism, and progressive fibros...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266968/ https://www.ncbi.nlm.nih.gov/pubmed/37325634 http://dx.doi.org/10.3389/fimmu.2023.1184252 |