Cargando…

Mechanism-based target therapy in primary biliary cholangitis: opportunities before liver cirrhosis?

Primary biliary cholangitis (PBC) is an immune-mediated liver disease characterized by cholestasis, biliary injuries, liver fibrosis, and chronic non-suppurative cholangitis. The pathogenesis of PBC is multifactorial and involves immune dysregulation, abnormal bile metabolism, and progressive fibros...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Yushu, He, XiaoSong, Rojas, Manuel, Leung, Patrick S. C., Gao, Lixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266968/
https://www.ncbi.nlm.nih.gov/pubmed/37325634
http://dx.doi.org/10.3389/fimmu.2023.1184252