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Mechanism-based target therapy in primary biliary cholangitis: opportunities before liver cirrhosis?

Primary biliary cholangitis (PBC) is an immune-mediated liver disease characterized by cholestasis, biliary injuries, liver fibrosis, and chronic non-suppurative cholangitis. The pathogenesis of PBC is multifactorial and involves immune dysregulation, abnormal bile metabolism, and progressive fibros...

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Detalles Bibliográficos
Autores principales:	Yang, Yushu, He, XiaoSong, Rojas, Manuel, Leung, Patrick S. C., Gao, Lixia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266968/ https://www.ncbi.nlm.nih.gov/pubmed/37325634 http://dx.doi.org/10.3389/fimmu.2023.1184252

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