Modulation of immune checkpoint regulators in interferon γ induced urothelial carcinoma and activated T-lymphocyte cells by cytostatics

Exploring the regulation of co-inhibitory (PD-1, PD-L1, CTLA-4) and co-stimulatory (CD28) genes by chemotherapeutic drugs is important for combined immune checkpoint blockade (ICB) therapy. ICB interferes with T-cell receptor and major histocompatibility complex (MHC) signaling by antibody drugs dir...

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Detalles Bibliográficos
Autores principales: Hänze, Jörg, Schulte-Herbrüggen, Johannes, Hofmann, Rainer, Hegele, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266969/
https://www.ncbi.nlm.nih.gov/pubmed/37138100
http://dx.doi.org/10.1038/s41435-023-00203-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266969/
https://www.ncbi.nlm.nih.gov/pubmed/37138100
http://dx.doi.org/10.1038/s41435-023-00203-0

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