Cargando…

Modulation of immune checkpoint regulators in interferon γ induced urothelial carcinoma and activated T-lymphocyte cells by cytostatics

Exploring the regulation of co-inhibitory (PD-1, PD-L1, CTLA-4) and co-stimulatory (CD28) genes by chemotherapeutic drugs is important for combined immune checkpoint blockade (ICB) therapy. ICB interferes with T-cell receptor and major histocompatibility complex (MHC) signaling by antibody drugs dir...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hänze, Jörg, Schulte-Herbrüggen, Johannes, Hofmann, Rainer, Hegele, Axel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266969/ https://www.ncbi.nlm.nih.gov/pubmed/37138100 http://dx.doi.org/10.1038/s41435-023-00203-0

Ejemplares similares

Co-Regulation of Immune Checkpoint PD-L1 with Interferon-Gamma Signaling is Associated with a Survival Benefit in Renal Cell Cancer
por: Hänze, Jörg, et al.
Publicado: (2020)

Cellular and soluble immune checkpoint signaling forms PD-L1 and PD-1 in renal tumor tissue and in blood
por: Keber, Corinna U., et al.
Publicado: (2022)

Sex-related differences in urothelial cell carcinoma of the bladder in Germany
por: Scheller, Thomas, et al.
Publicado: (2018)

Epithelial mesenchymal transition status is associated with anti-cancer responses towards receptor tyrosine-kinase inhibition by dovitinib in human bladder cancer cells
por: Hänze, Jörg, et al.
Publicado: (2013)

Chemotherapy of Locally Advanced or Metastatic Urothelial Cell Carcinoma: Monocentric Real-Life Data
por: Fischer, Christine, et al.
Publicado: (2020)

Changes in prostaglandin E2 in patients with idiopathic overactive bladder syndrome after botulinum toxin type A treatment: is there a clinical benefit?
por: Hegele, Axel, et al.
Publicado: (2014)

Interferon γ Is Required for Activation-induced Death of T Lymphocytes
por: Refaeli, Yosef, et al.
Publicado: (2002)

Soluble PD-L1 in blood correlates positively with neutrophil and negatively with lymphocyte mRNA markers and implies adverse sepsis outcome
por: Derigs, Marcus, et al.
Publicado: (2022)

Immune checkpoint inhibitors for urothelial carcinoma
por: Kim, Hyung Suk, et al.
Publicado: (2018)

Direct AKT activation in tumor-infiltrating lymphocytes markedly increases interferon-γ (IFN-γ) for the regression of tumors resistant to PD-1 checkpoint blockade
por: Santinon, François, et al.
Publicado: (2022)

Interferon γ is required for activation-induced death of T lymphocytes
por: Refaeli, Yosef, et al.
Publicado: (2012)

T lymphocyte-targeted immune checkpoint modulation in glioma
por: Kelly, William James, et al.
Publicado: (2020)

Tuberculin skin test and interferon‐γ release assays: Can they agree?
por: Santos, João Almeida, et al.
Publicado: (2022)

G-quadruplex binders as cytostatic modulators of innate immune genes in cancer cells
por: Miglietta, Giulia, et al.
Publicado: (2021)

Suppression of Lymphoma and Epithelial Malignancies Effected by Interferon γ
por: Street, Shayna E.A., et al.
Publicado: (2002)

Involvement of Tweak in Interferon γ–Stimulated Monocyte Cytotoxicity
por: Nakayama, Masafumi, et al.
Publicado: (2000)

Immune Checkpoint Inhibitors in the Management of Urothelial Carcinoma
por: Patel, Aakash, et al.
Publicado: (2021)

Interleukin-10 and Interferon-γ Levels in Patients with Cutaneous Leishmaniasis Treated with Cryotherapy
por: Handjani, Farhad, et al.
Publicado: (2017)

Elevated Spontaneous Interferon-γ Secretion in Human Immunodeficiency Virus-Infected Persons
por: Sparks, Rachel, et al.
Publicado: (2017)

Trends in Checkpoint Inhibitor Therapy for Advanced Urothelial Cell Carcinoma at the End of Life: Insights from Real‐World Practice
por: Parikh, Ravi B., et al.
Publicado: (2019)

Induction of γ‐Interferon by Avarol in Human Peripheral Blood Lymphocytes
por: Voth, Rita, et al.
Publicado: (1988)

Deficiencies of GM-CSF and Interferon γ Link Inflammation and Cancer
por: Enzler, Thomas, et al.
Publicado: (2003)

Correction: T lymphocyte-targeted immune checkpoint modulation in glioma
Publicado: (2020)

INTERACTION OF AGGREGATED γ-GLOBULIN WITH B LYMPHOCYTES
por: Dickler, H. B., et al.
Publicado: (1972)

Chronic liver inflammation dominated by interferon-γ can prevent hepatocarcinogenesis
por: Schrader, Jörg, et al.
Publicado: (2012)

Disseminated Talaromyces marneffei and Mycobacterium abscessus in a Patient With Anti-Interferon-γ Autoantibodies
por: Pruetpongpun, Nattapol, et al.
Publicado: (2016)

Differences in Clinical Manifestations according to the Positivity of Interferon-γ Assay in Patients with Intestinal Tuberculosis
por: Jung, Hye Jin, et al.
Publicado: (2016)

Spindle checkpoint proteins Mad1 and Mad2 are required for cytostatic factor–mediated metaphase arrest
por: Tunquist, Brian J., et al.
Publicado: (2003)

The Evolution of Immune Checkpoint Inhibitors in Advanced Urothelial Carcinoma
por: Houssiau, Hélène, et al.
Publicado: (2022)

Longitudinal Evaluation of Circulating Tumor DNA Using Sensitive Amplicon-Based Next-Generation Sequencing to Identify Resistance Mechanisms to Immune Checkpoint Inhibitors for Advanced Urothelial Carcinoma
por: Ravi, Praful, et al.
Publicado: (2022)

Moderate Exercise Enhances the Production of Interferon-γ and Interleukin-12 in Peripheral Blood Mononuclear Cells
por: Zamani, Alireza, et al.
Publicado: (2017)

Diagnostic and Therapeutic Challenges in Disseminated Mycobacterium colombiense Infection Caused by Interferon-γ Neutralizing Autoantibodies
por: Matono, Takashi, et al.
Publicado: (2023)

Autocrine Secretion of Interferon γ Negatively Regulates Homing of Immature B Cells
por: Flaishon, Liat, et al.
Publicado: (2000)

Intrathecal Chemotherapy: Selection of Cytostatic Agents
por: Hayakawa, T., et al.
Publicado: (1970)

The cytostatic activity of cultured Kupffer cells.
por: Pulford, K., et al.
Publicado: (1985)

Biomarkers of the Response to Immune Checkpoint Inhibitors in Metastatic Urothelial Carcinoma
por: Chen, Siteng, et al.
Publicado: (2020)

Combination Biomarker of Immune Checkpoints Predict Prognosis of Urothelial Carcinoma
por: Tsai, Chung-Ying, et al.
Publicado: (2021)

Predictive biomarkers for immune checkpoint inhibitor response in urothelial cancer
por: Parent, Pauline, et al.
Publicado: (2023)

Interferon-γ derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity
por: Bhat, Purnima, et al.
Publicado: (2017)

Contrasting the impact of cytotoxic and cytostatic drug therapies on tumour progression
por: Anttila, Jani V., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_gi76h20b9to0b84im902uc4i7j