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αCGRP deficiency aggravates pulmonary fibrosis by activating the PPARγ signaling pathway

In order to explore whether αCGRP (Calca) deficiency aggravates pulmonary fibrosis (PF). Clinical data from patients with PF (n = 52) were retrospectively analyzed. Lung tissue from a bleomycin (BLM)-induced rat model was compared with that of Calca-knockout (KO) and wild type (WT) using immunohisto...

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Detalles Bibliográficos
Autores principales: Lv, Xiaoting, Chen, Qingquan, Zhang, Zewei, Du, Kaili, Huang, Yaping, Li, Xingzhe, Zeng, Yiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266974/
https://www.ncbi.nlm.nih.gov/pubmed/37231189
http://dx.doi.org/10.1038/s41435-023-00206-x