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A pan-influenza antibody inhibiting neuraminidase via receptor mimicry

Rapidly evolving influenza A viruses (IAVs) and influenza B viruses (IBVs) are major causes of recurrent lower respiratory tract infections. Current influenza vaccines elicit antibodies predominantly to the highly variable head region of haemagglutinin and their effectiveness is limited by viral dri...

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Detalles Bibliográficos
Autores principales: Momont, Corey, Dang, Ha V., Zatta, Fabrizia, Hauser, Kevin, Wang, Caihong, di Iulio, Julia, Minola, Andrea, Czudnochowski, Nadine, De Marco, Anna, Branch, Kaitlin, Donermeyer, David, Vyas, Siddhant, Chen, Alex, Ferri, Elena, Guarino, Barbara, Powell, Abigail E., Spreafico, Roberto, Yim, Samantha S., Balce, Dale R., Bartha, Istvan, Meury, Marcel, Croll, Tristan I., Belnap, David M., Schmid, Michael A., Schaiff, William Timothy, Miller, Jessica L., Cameroni, Elisabetta, Telenti, Amalio, Virgin, Herbert W., Rosen, Laura E., Purcell, Lisa A., Lanzavecchia, Antonio, Snell, Gyorgy, Corti, Davide, Pizzuto, Matteo Samuele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10266979/
https://www.ncbi.nlm.nih.gov/pubmed/37258672
http://dx.doi.org/10.1038/s41586-023-06136-y