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From bench to bedside: (64)Cu/(177)Lu 1C1m-Fc anti TEM-1: mice-to-human dosimetry extrapolations for future theranostic applications

The development of diagnostic and therapeutic radiopharmaceuticals is an hot topic in nuclear medicine. Several radiolabeled antibodies are under development necessitating both biokinetic and dosimetry extrapolations for effective human translation. The validation of different animal-to-human dosime...

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Detalles Bibliográficos
Autores principales: Gnesin, Silvano, Chouin, Nicolas, Cherel, Michel, Dunn, Steven Mark, Schaefer, Niklaus, Faivre-Chauvet, Alain, Prior, John O., Delage, Judith Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267050/
https://www.ncbi.nlm.nih.gov/pubmed/37314509
http://dx.doi.org/10.1186/s13550-023-01010-4