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Intravenous and oral whole body ketone dosimetry, biodistribution, metabolite correction and kinetics studied by (R)-[1-(11)C]β-hydroxybutyrate ([(11)C]OHB) PET in healthy humans

BACKGROUND: Ketones are increasingly recognized as an important and possibly oxygen sparing source of energy in vital organs such as the heart, the brain and the kidneys. Drug treatments, dietary regimens and oral ketone drinks designed to deliver ketones for organ and tissue energy production have...

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Detalles Bibliográficos
Autores principales: Luong, Thien Vinh, Nielsen, Erik Nguyen, Falborg, Lise, Kjærulff, Mette Louise Gram, Tolbod, Lars Poulsen, Søndergaard, Esben, Møller, Niels, Munk, Ole Lajord, Gormsen, Lars Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267081/
https://www.ncbi.nlm.nih.gov/pubmed/37314530
http://dx.doi.org/10.1186/s41181-023-00198-z