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Intact mass analysis reveals the novel O-linked glycosylation on the stalk region of PD-1 protein
Programmed cell death protein 1 (PD-1) is a key receptor in the immune checkpoint pathway and has emerged to be a promising target for cancer therapy. PD-1 consists of an intracellular domain followed by a transmembrane domain that is connected to the extracellular domain by the stalk region. Althou...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267102/ https://www.ncbi.nlm.nih.gov/pubmed/37316505 http://dx.doi.org/10.1038/s41598-023-36203-3 |