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Mitochondrial complex III activity: from invasive muscle biopsies to patient-friendly buccal swab analysis

Drug-induced mitochondrial dysfunction is a common adverse effect, particularly in case of statins—the most prescribed drugs worldwide. These drugs have been shown to inhibit complex III (CIII) of the mitochondrial oxidative phosphorylation process, which is related to muscle pain. As muscle pain is...

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Detalles Bibliográficos
Autores principales: Somers, Tim, Allard, Neeltje A. E., Siddiqi, Sailay, Janssen, Margit C. M., Hopman, Maria T. E., Morshuis, Wim J., Russel, Frans G. M., Timmers, Silvie, Schirris, Tom J. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267125/
https://www.ncbi.nlm.nih.gov/pubmed/37316639
http://dx.doi.org/10.1038/s41598-023-36741-w