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Senescent cardiomyocytes contribute to cardiac dysfunction following myocardial infarction
Myocardial infarction is a leading cause of morbidity and mortality. While reperfusion is now standard therapy, pathological remodelling leading to heart failure remains a clinical problem. Cellular senescence has been shown to contribute to disease pathophysiology and treatment with the senolytic n...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267185/ https://www.ncbi.nlm.nih.gov/pubmed/37316516 http://dx.doi.org/10.1038/s41514-023-00113-5 |