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Senescent cardiomyocytes contribute to cardiac dysfunction following myocardial infarction

Myocardial infarction is a leading cause of morbidity and mortality. While reperfusion is now standard therapy, pathological remodelling leading to heart failure remains a clinical problem. Cellular senescence has been shown to contribute to disease pathophysiology and treatment with the senolytic n...

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Detalles Bibliográficos
Autores principales: Redgrave, Rachael E., Dookun, Emily, Booth, Laura K., Camacho Encina, Maria, Folaranmi, Omowumi, Tual-Chalot, Simon, Gill, Jason H., Owens, W. Andrew, Spyridopoulos, Ioakim, Passos, João F., Richardson, Gavin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267185/
https://www.ncbi.nlm.nih.gov/pubmed/37316516
http://dx.doi.org/10.1038/s41514-023-00113-5