Simultaneous reduction of all ORMDL proteins decreases the threshold of mast cell activation

In mammals, the ORMDL family of evolutionarily conserved sphingolipid regulators consists of three highly homologous members, ORMDL1, ORMDL2 and ORMDL3. ORMDL3 gene has been associated with childhood-onset asthma and other inflammatory diseases in which mast cells play an important role. We previous...

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Detalles Bibliográficos
Autores principales: Demkova, Livia, Bugajev, Viktor, Utekal, Pavol, Kuchar, Ladislav, Schuster, Björn, Draber, Petr, Halova, Ivana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267218/
https://www.ncbi.nlm.nih.gov/pubmed/37316542
http://dx.doi.org/10.1038/s41598-023-36344-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267218/
https://www.ncbi.nlm.nih.gov/pubmed/37316542
http://dx.doi.org/10.1038/s41598-023-36344-5

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